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Portada del sitio > Documentos > Estudios Científicos > Biomonitoring of estrogen and melatonin metabolites among women residing (...)

J Occup Environ Med. 2007 Oct;49(10):1149-56.

Biomonitoring of estrogen and melatonin metabolites among women residing near radio and television broadcasting transmitters.

Jueves 22 de noviembre de 2007 · 1751 lecturas

Biomonitoring of estrogen and melatonin metabolites among women residing near radio and television broadcasting transmitters.

Clark ML, Burch JB, Yost MG, Zhai Y, Bachand AM, Fitzpatrick CT, Ramaprasad J, Cragin LA, Reif JS.

Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA.

OBJECTIVES: Metabolites of estrogen (estrone-3-glucuronide [E1G]) and melatonin (6-hydroxymelatonin sulfate [6-OHMS]) were characterized among women living in a community with increased radiofrequency (RF) exposure from radio and television transmitters. METHODS: RF spot measurements, and personal 60-Hz magnetic field and residential parameters were collected. Overnight urine samples were assayed for E1G and 6-OHMS excretion. RESULTS: Among premenopausal women, there were no associations between RF or 60-Hz nonionizing radiation and E1G or 6-OHMS excretion. Among postmenopausal women, increased residential RF exposures, transmitter proximity and visibility, and temporally stable 60-Hz exposures were significantly associated with increased E1G excretion. This association was strongest among postmenopausal women with low overnight 6-OHMS levels. CONCLUSIONS: RF and temporally stable 60-Hz exposures were associated with increased E1G excretion among postmenopausal women. Women with reduced nocturnal 6-OHMS excretion may represent a sensitive subgroup.

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