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Portada del sitio > Documentos > Estudios Científicos > EFFECT OF GSM MOBILE PHONE RADIATION ON BLOOD-BRAIN BARRIER

EFFECT OF GSM MOBILE PHONE RADIATION ON BLOOD-BRAIN BARRIER

Viernes 18 de noviembre de 2005 · 2010 lecturas

EFFECT OF GSM MOBILE PHONE RADIATION ON BLOOD-BRAIN BARRIER
Dariusz Leszczynski
Bio-NIR Research Group, Radiobiology Laboratory, STUK-Radiation and Nuclear Safety Authority, Helsinki,
Finland; dariusz.leszczynski stuk.fi
ABSTRACT
Some animal studies have suggested that mobile phone radiation may cause increase in blood-brain barrier
permeability. We have hypothesized (Leszczynski et al. Differentiation, 70, 2002, in press) that the mobile phone
radiation-induced increased expression and phosphorylation (activity) of stress protein hsp27 might be the molecular
mechanism regulating blood-brain barrier permeability and, possibly, cell apoptosis. Here we present evidence
suggesting that mobile phone radiation indeed affects hsp27-dependent cytoplasmic distribution of F-actin and stability
of stress fibers. This observation supports our hypothesis that mobile phone radiation-induced changes in hsp27
expression/activity might eventually lead to increase in the permeability of blood-brain barrier.

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